Release Notes

  • Version 3.1.4 was released on September 13, 2012.
    • Fixed an issue with the estimate of the next dose not being rounded down when the next dose should decrease.
    • Fixed the display in the tree of doses to show non-integer values when the minimum dose increment is 0.
    • When the doses listed in the input data file in the main dialog are outside the range of the minimum and maximum dose listed in the dialog window the program will show an error message and stop execution.

  • Version 3.1.3 was released on June 29, 2012.
    • Fixed a rounding issue with the minimum dose increment in the main dialog where the dose was being rounded to the nearest increment rather than to the greatest increment that is less than or equal to the estimated dose.
    • The cohort size is now incorporated in the optional sequence of no DLTs in the main dialog.
    • The version number is no longer included in the application name.
    • The file that is downloaded with the package should no longer provide an inappropriate path name to the main dialog window.

  • Version 3.1.2 was released on May 31, 2012.
    • Corrected the sequence of no DLTs in the main dialog to work with both a fixed and a variable alpha, depending on whether the box for Variable Alpha Increment is checked or not.

  • Version 3.1.1 was released on May 23, 2012.
    • The update includes more detailed output for the sequence of no DLTs in the dialog and simulation. The output from the main dialog now includes information on trial parameters under which the sequence was run: theta, minimum dose and maximum dose. The tables from both the main dialog and the simulation now also include the percent change from previous dose and the value of alpha, in addition to the dose.

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