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documentation User Guide (HTML)(PDF)
Tutorial (PDF)
⊢ Protocol Template (MS Word) (MS Word Doc)
⊢⊢ Protocol References (EndNote)

download EWOC - Standalone

contact us E-mail

Link EWOC CRAN Packages

release notes Details about changes in the Web-EWOC 1.8.1

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Release Notes

  • Version 1.8.1 was released on June 21, 2023.
    • Migrated from Google Universal Analytics to Google Analytics 4
  • Version 1.8.0 was released on December 13, 2021.
    • Added Drug Combination (Two agents) method with R + Jags implementation
      • Added Probability of DLT at the Minimum Dose of Drug A and Maximum Dose of Drug B (ρ01)
      • Added Probability of DLT at the Maximum Dose of Drug A and Minimum Dose of Drug B (ρ10)
      • Added Probability of DLT at the Minimum Dose of Drug A and Drug B given ρ01 and ρ10 (ρ00 / min(ρ01, ρ10) | (ρ01, ρ10))
      • Added Interaction between Drug A and Drug B (η)
    • Added DLT/Dose Matrix CSV download
    • Bug fixes
    • Updated User Guide to 1.8
    • Updated footer to version 1.8
  • Version 1.7.1 was released on November 13, 2017.
    • Added EWOC CRAN packages link under Links
    • Updated About us
    • Updated footer to version 1.7.1
  • Version 1.7 was released on January 20, 2017.
    • Added Trial Simulation running type to Time-to-Event-EWOC method
    • Bug fixes: Input K matrix
    • Bug fixes: Extended prior, Probability of DLT at Minimum Dose
    • Bug fixes: Optional tab, display error
    • Updated User Guide to 1.7
    • Updated footer to version 1.7
  • Version 1.6 was released on July 29, 2016.
    • Added new parameter labeled "Starting Dose" for Continuous and Discrete Doses in Trial Simulation
    • Added new input fields of Variable Alpha Increment and Increase Alpha in Dose Computation and Trial Simulation
    • Added new alpha/patient table in the Result PDF
    • Bug fixes: Probability of DLT at Minimum Dose between upper and lower bond
    • Bug fixes: Database subtask issues
    • Updated User Guide to 1.6
    • Updated footer to version 1.6
  • Version 1.5 was released on January 13, 2016.
    • Added Time-to-Event EWOC method with R + Fortran implementation
    • Bug fixes: upload data file and data matrix
    • Bug fixes: M2/M4/M3/M5 plot prior density and database saved project
    • Bug fixes: R+Fortran simulations
    • About Us development team update
    • Updated recovery email with reply email address
    • Updated User Guide to 1.5
    • Updated footer to version 1.5
  • Version 1.4 was released on July 30, 2014.
    • Added advanced Simulation Extended Priors for M2, M4, M3, M5 in Simulation
    • Extended Priors implementation in R+Fortran and R+OpenBugs
    • Bug fixes: enhanced calculation flow, registration and validation.
    • Updated User Guide to 1.4
    • Updated footer to version 1.4
  • Version 1.3 was released on October 22, 2013.
    • Added advanced computation Extended Priors for M2, M4, M3, M5
    • Extended Priors implementation in R+Fortran and R+OpenBugs
    • Improve delete function in project and task
    • Bug fixes
    • Updated bio links
    • Updated User Guide to 1.3
    • Updated footer to version 1.3
  • Version 1.2.1 was released on June 6, 2013.
    • User guide (PDF + Html) and Tutorial (PDF) update
    • links update
  • Version 1.2 was released on May 20, 2013
    • Added Simulation option to "Select running type"
    • Added Next Dose and Simulation options to "Select running type"
    • Added Simulation menu tabs
    • Removed "Perform calculations online or offline" from general setting
    • Added "Select Running type" and "Select implementation" information to the report file
    • Removed Program mode, Algorithm and Running mode from Saved Project
    • Rearranged columns in Saved Project
    • Updated text from Initial Dose to Minimum Dose (ρ0)
    • Updated validation condition for Probability of DLT at Minimum Dose must be greater than 0
    • Add a new Database table to store simulation parameters
    • Removed the format/rounding inside of Minimum.Dose.Increment function
    • Added format/digits control in other places for display purposes: next recommended dose, report, marginal density plot, tree of doses etc
    • Increased the precision by 2 in openbugs sampling
    • Added new summary statistics and tables for simulation results in the report file
    • Updated help manual in PDF and HTML from v1.1 to v1.2
    • "Back to Top" clicks in Help menu.
    • Added documentation, Tutorial, Protocol Template, and Protocol References
    • Updated footer to version 1.2
  • Version 1.1.1 was released on November 13, 2012.
    • Implemented Google Analytics
  • Version 1.1 was released on November 02, 2012.
    • Default demo to R + Fortran method
    • Added R + Fortran method option
    • Made Tree of Doses for next cohort optional
    • Made Sequence of doses with no DLTs optional
    • Made Number of doses in sequence optional
    • Changed report format to PDF files
    • Changed Mean to Mode in beta prior
    • Updated help manual in PDF and HTML from v1.0 to v1.1
    • Added release notes and help menu to public
    • Modified and add more field to the database
    • Fixed bugs:
      • Fixed the display content in parameters file in the result tab
      • Corrected the function to calculate the beta parameter from mode and standard deviation
      • Normalized the y-scale in the marginal posterior density plot
      • Fixed several display bugs
  • Version 1.0 was released on October 10, 2012.
    • Basic EWOC functions

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